Chain Reaction is not a mass-participation event; instead it concentrates on selected individuals who want the physical challenge. In return, they benefit from valuable networking opportunities and the immense satisfaction of directly helping sick children through charities such as the Starlight Children’s Foundation, Monash Children and Brisbane Royal Children's Hospital Foundation and the Victor Chang Research Institute.
In 2012 there will be a Chain Reaction Challenge in Victoria, New South Wales and Queensland with the three events targeting a total annual raise of $3 million.